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AMH blood test- everything you wanted to know about this common blood test but were afraid to ask

AMH testing, a Q&A: Princeton IVF blog
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Common questions and answers about AMH testing

What is AMH?

Antimullerian hormone, commonly known at AMH, is hormone that is secreted by follicles in the ovary. It was initially studied for its role in reproductive development but is now widely used as a test of ovarian reserve.

What is ovarian reserve?

Ovarian reserve is a measure of the aging of the ovaries, and how many eggs the ovaries are likely to produce when given fertility medications. AMH, day 3 FSH and estradiol levels and antral follicle counts on ultrasound are commonly used measures of ovarian reserve.

What does a low AMH level mean?

A low AMH level, which most doctors consider a level of less than one, indicates that the ovary has fewer eggs available to stimulate. Women with low AMH levels, will usually make fewer eggs when given fertility drugs for IVF or insemination cycles.

Does a low AMH level mean that I am less likely to get pregnant?

AMH is a great test to determine how a woman will respond to medications, but it not as good at predicting pregnancy rates. It is true that women who produce more eggs are more likely to get pregnant, but particularly in young women, who do not need a large number of eggs, there does not seem to be reason to be concerned.

What does a high AMH level mean?

A high AMH level suggests that you are likely to respond very well to fertility injections and may be more likely to become hyperstimulated when taking them. It is also is considered a sign of polycystic ovaries (PCO) although AMH levels are not currently used to make the diagnosis.

Can the AMH level be used to predict if I will have trouble getting pregnant in the future?

Not really. Despite the early hope that AMH could help women know in advance if they might have infertility in the future, it turns out there is no evidence that AMH can predict future fertility.

Red wine, Resveratrol and PCOS

Could a chemical in red wine help you if you have PCOS: Princeton IVF blog

Could one of the compounds found in red wine help women with PCOS?

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Yes, it actually might help women with polycystic ovarian syndrome.

What is resveratrol?

Reservatrol belongs to a group of chemicals call polyphenols which are commonly thought to act as antioxidants. It is found in the skin of grapes, as well is in peanuts and some berries. Most resveratrol supplements sold in the US, actually come from a plant grown in Asia, rather than from grapes. It has been used as a supplement to help inflammation and diabetes.

Why might resveratrol be helpful for with PCOS?

Polycystic ovarian syndrome is the most common hormone disorder in women of reproductive age, and a common cause for infertility. The symptoms of PCOS are largely related to irregular cycles and excess levels of male-like hormones, but the underlying cause is related to how the body handles sugars. Most women with PCOS have a condition called insulin resistance as the reason for their disorder, and diabetes drugs such as Metformin are commonly used as treatment.  Since resveratol can help women with diabetes, it is possible that it may help women with PCOS as well.

A new study suggests resveratrol may be helpful.

Researchers at University of California- San Diego took women with confirmed PCOS and gave them resveratol supplements to see what would happen. They found that these patient's levels of male hormone including testosterone dropped significantly, suggesting that resveratrol may be doing this by reducing insulin resistance. The researchers did not look at whether their cycles became more irregular or more fertility.

So, should I start drinking red wine if I have PCOS and want to get pregnant?

Not a great idea, at least when you are or might be pregnant. It is possible (but still unproven at this time) that resveratrol may help promote fertility in women with PCOS. On the other hand, it is well known that alcohol, including red wine, when consumed by pregnant women can increase the risk of serious birth defects. It may be reasonable to have red wine before conception, but no OBGYN or  Fertility Specialist would recommend you drink once you might be pregnant.