NSAID

Pain medicine and miscarriage

NSAIDS and miscarriage risk: Princeton IVF blog

Opioid pain medications are making all the headlines, but are over the counter pain medications really safe?


New research suggests that taking over the counter pain meds could increase the risk of miscarriage.

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California researchers tried to determine whether using over the counter pain medications such as acetominophen (Tylenol) and non steroidal anti-inflammatories ( such as ibuprofen, Motrin or Advil) might affect the risk of miscarriage. They studied almost 1100 pregnant women, comparing those women who took no pain medications to those who took acetaminophen, those who took non-steroidal and those who took both.

What they found was interesting…

  • Women who took tylenol or NSAIDs such as ibuprofen were more likely to miscarry that those who did not

  • Taking this medications around ovulation appeared to be the riskiest

  • Women who used these drugs for longer periods of time were at the greatest risk

  • Thin women were more at risk than overweight women

So, what does this all mean…

  • It does not mean that over the counter pain medications actually cause miscarriages, just that women who take them for whatever reason are more likely to miscarry.

  • It is a good idea to avoid Tylenol, Motrin, Alleve and other over the counter pain medications around the time of ovulation is you are trying to have a baby